P16 gene is located on the 9p21 chromosome and is a tumor suppressor gene. P16 gene deletion is present in 10% of ALL patients and has a higher proportion in T-ALL. Currently, FISH technology is widely used in the diagnosis of P6 gene deletion in ALL.
P16 gene deletion probe uses an orange-red dye to label P16 gene region, and a green dye is to label chromosome 9 centromere region (CEP9).
One of the most common abnormalities in ALL is that homozygous deletions are mostly in T-ALL, and the proportion of homozygotes and heterozygotes in B-ALL is comparable; the prognosis is poor.
Product size: 100μL FISH probe ( ⬤ | ⬤ ) + Pretreatment reagent (10 tests) + Antifade staining solution DAPI (10 tests).