Kit de sondas de detección de LA deleción 7q (brazo largo del cromosoma 7)
7q chromosome deletion detection probe kit
Deletion of the entire chromosome 7 or deletion of the long arm 7q is a recurrent abnormality in MDS, and its incidence is about 15% in patients with MDS.
Probe description
7q chromosome deletion probe labels the 7q22 region with an orange-red dye and the D7S486 region with a green dye.
Clinical significance
Patients with 7q-deficient have a MDS poor prognosis and are prone to infection and conversion to white blood cells (leukocytes).
References
Coleman JF, et al. (2011) Am J Clin Pathol 135: 915-20.